This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor Clq.

SELP / P-Selectin / CD62P selectin P (granule membrane protein 140kDa, antigen CD62) SELP encodes a 140 kD protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells.

2 days ago P-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene. [5] P-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets . P-Selectin (CD62P), previously termed PADGEM or GMP-140, is a single chain glycoprotein of 140 kDa expressed in platelets and endothelial cells. In platelets, P-selectin is stored in α granules, whereas in endothelial cells it is found in Weibel–Palade bodies. P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling.

P selectin

Viruses 医学与生命科学. Epithelial Cells 医学与生命科学. Virology P-selectin är en adhesionsmolekyl som uttrycks på aktiverade trombocyter och befrämjar kontakt med vita blodkroppar. NO är ett kroppseget ämne som har P-Selectin. engelska.

Pendu, R., Terraube, V., Christophe, O. D., Gahmberg, C. G., de Groot, P. G., Lenting, P. J., & Denis, C. V. (2006). P-selectin glycoprotein ligand 1 and beta

P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. Definition of p-selectin in the Definitions.net dictionary. Meaning of p-selectin. What does p-selectin mean?

P-selectin, the largest selectin, is stored in α-granules of platelets and in Weibel–Palade bodies of endothelial cells, and is translocated to the cell surface of activated endothelial cells and platelets. E-selectin is not expressed under baseline conditions, except in skin microvessels, but is rapidly induced by inflammatory cytokines.

With high purity, high biological activity, high stability, and other superior features, you can use this Human P-Selectin protein for relevant bioassay and related research.

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The R-PLEX platform offers matched sets of antibodies and calibrators for a wide menu of biomarkers. The R-PLEX Human P-Selectin Antibody Set can be used with other MSD components (see "Recommended Components" tab below) to build assays that measure P-Selectin.

Search and download thousands of Swedish university dissertations. Full text. Free. Antigensymbol, P-Selectin.
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SELP / P-Selectin / CD62P selectin P (granule membrane protein 140kDa, antigen CD62) SELP encodes a 140 kD protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells.

With high purity, high biological activity, high stability, and other superior features, you can use this Human P-Selectin protein for relevant bioassay and related research. Upon injury in a blood vessel, platelets become activated and adbere to prevent blood loss. Activated platelets express adhesion molecules on their surface that also make leukocytes adhere to the i This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor Clq. Mangell, Peter et al. "Critical role of P-selectin-dependent leukocyte recruitment in endotoxin-induced intestinal barrier dysfunction in mice.". Inflammation Research. 2007, 56(5). 189-194.

2018-11-16

Free. Antigensymbol, P-Selectin. Antikroppstyp, Primary. Klonalitet, Monoclonal. Konjugation, Unconjugated.

E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The R-PLEX platform offers matched sets of antibodies and calibrators for a wide menu of biomarkers. The R-PLEX Human P-Selectin Antibody Set can be used with other MSD components (see "Recommended Components" tab below) to build assays that measure P-Selectin. Recombinant Human P-Selectin/CD62P Fc Chimera Protein, CF (137-PS) View all 12 R&D Systems SELP (P-Selectin/CD62P) Primary Antibodies. Human P-Selectin/CD62P Antibody (BBA30) Human P-Selectin/CD62P Fluorescein-conjugated Antibody (BBA34) View all 2 R&D Systems SELP (P-Selectin/CD62P) ELISAs. Human P-Selectin/CD62P Quantikine ELISA Kit (DPSE00) P-selectin that is expressed on the surface of the endothelium mediates abnormal rolling and static adhesion of sickle erythrocytes to the vessel surface in vitro.